Quantitative Dixon-Based PDFF and R2* Estimation and Optimization on MR-Simulation and MR-Linac Devices for the Pelvis and Head and Neck: A Prospective R-IDEAL Stage 0-2a Study
This prospective R-IDEAL Stage 0-2a study demonstrates that a 6-point quantitative Dixon sequence offers superior geometric accuracy, quantitative concordance, and reproducibility for PDFF and R2* estimation across 1.5T and 3T MR-Simulation and MR-Linac devices compared to 2- and 3-point methods, thereby validating its use for adaptive radiation therapy and bone marrow characterization in the pelvis and head and neck.
McCullum, L., West, N. A., Shin, K., Taylor, B. A., Augustyn, A., Saifi, O., Thrower, S., Wang, J., Shah, S., Choi, S., Anakwenze, C. P., Fuller, C. D., Floyd, W.2026-03-10📄 radiology and imaging